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A. Yes. The typical cold lasts just seven to nine days, with people usually feeling the worst on days two to four, says Priya Wagle, M.D., an ear, nose and throat specialist in private practice in Linwood, New Jersey. "If you experience symptoms for a longer period of time, check with your doctor to be sure you don't have something more serious, like a sinus infection. A cold is a virus, so antibiotics won't help, but sinusitis can be bacterial and is treated with a prescription."